Single-cell sequencing is a new technology for amplifying and sequencing the DNA/RNA at single cell level. The principle is to use MDA or MALBAC to amplify the DNA/RNA in isolated single cells efficiently, and carry out NGS. Bioinformatics analysis can obtain the information of genetic variation in cells, which can be used to reveal cell population difference and cell evolution. Single-cell genomics will help to uncover cell lineage relationships; single-cell transcriptomics will supplant the coarse notion of marker-based cell types; and single-cell epigenomics and proteomics will allow the functional states of individual cells to be analyzed.
CD Genomics proprietary GenSeqTM Technology provides comprehensive Single-Cell Sequencing services. These global gene expression patterns in single cells already have dramatically advanced cell biology.
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